MDS Analytical: CellKey™ – High Throughput
Secondary Screening Instrument
CellKey™ is a high information secondary screening instrument enabling label-free, real-time cell-based functional analysis of endogenous receptors.
- Client
- MDS Sciex
- Product
- CellKey™
Our Ingenuity
We provided the instrument development and transfer to manufacture for the world's first cellular dielectric spectrometer
Our role included:
- Concept generation
- Hardware development (analyser, fluidics, robotics, heating)
- Software for control and service
- Prototype build, test and qualification
- Design verification
- Transfer to manufacture
Challenges included:
- Fluid handling
- High performance impedance measurement
- Temperature control
- Cell plate handling
- Transfer to manufacture in Singapore
Your Advantage
The end result:
- Performs high sensitivity label-free measurements of real time cellular response to drug candidates
- Uses custom 96 well microplates with sensing elements in each well to directly measure cell impedance changes
- Interfaces to laboratory automation (microplates and disposables in pop-out draws)
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